| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dihydrolipoyl dehydrogenase |
|---|
| Ligand | BDBM32062 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Inhibition Assay |
|---|
| pH | 7±n/a |
|---|
| IC50 | 520±70 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Wong, C; Wu, Y Compounds and methods for treating tuberculosis infection US Patent US9073941 Publication Date 7/7/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Dihydrolipoyl dehydrogenase |
|---|
| Name: | Dihydrolipoyl dehydrogenase |
|---|
| Synonyms: | DLDH_MYCTU | Lipoamide Dehydrogenase (Lpd) | lpd | lpdC |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 49231.98 |
|---|
| Organism: | Mycobacterium tuberculosis |
|---|
| Description: | P9WHH9 |
|---|
| Residue: | 464 |
|---|
| Sequence: | MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLNVGCIPSKALLRNAELVH
IFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADANT
LLVDLNDGGTESVTFDNAIIATGSSTRLVPGTSLSANVVTYEEQILSRELPKSIIIAGAG
AIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFKKLGVTILTATKVESIAD
GGSQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDKAGVALTDRKAIGVDDYMRTN
VGHIYAIGDVNGLLQLAHVAEAQGVVAAETIAGAETLTLGDHRMLPRATFCQPNVASFGL
TEQQARNEGYDVVVAKFPFTANAKAHGVGDPSGFVKLVADAKHGELLGGHLVGHDVAELL
PELTLAQRWDLTASELARNVHTHPTMSEALQECFHGLVGHMINF
|
|
|
|---|
| BDBM32062 |
|---|
| n/a |
|---|
| Name | BDBM32062 |
|---|
| Synonyms: | MLS000054842 | N-(1-butyl-3-cyano-2-pyrrolo[3,2-b]quinoxalinyl)benzamide | N-(1-butyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)benzamide | N-(1-butyl-3-cyanopyrrolo[3,2-b]quinoxalin-2-yl)benzamide | SMR000060333 | US9045483, 3 | US9073941, 1003 | cid_1910302 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H19N5O |
|---|
| Mol. Mass. | 369.4192 |
|---|
| SMILES | CCCCn1c(NC(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc12 |
|---|
| Structure | 
|
|---|
Search and Browse
