Reaction Details | |||
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Report a problem with these data | |||
Target | Kappa-type opioid receptor | ||
Ligand | BDBM156570 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | OPRK1 antagonist assay | ||
Temperature | 298.15±n/a K | ||
IC50 | 0.97±n/a nM | ||
Comments | extracted | ||
Citation | Roberts, E; Guerrero, MA; Urbano, M; Rosen, H Kappa opioid ligands US Patent US9682966 Publication Date 6/20/2017 | ||
More Info.: | Get all data from this article, Assay Method | ||
Kappa-type opioid receptor | |||
Name: | Kappa-type opioid receptor | ||
Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 42648.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41145 | ||
Residue: | 380 | ||
Sequence: |
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BDBM156570 | |||
n/a | |||
Name | BDBM156570 | ||
Synonyms: | US10118915, Compound 350 | US9682966, 350 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H33N5O | ||
Mol. Mass. | 419.5624 | ||
SMILES | CC1CCC(CC1)NC1CCN(CC1)c1nc2ccc(C)cc2cc1-c1nc(C)no1 |(8.67,-.62,;7.34,-1.39,;7.34,-2.93,;6,-3.7,;4.67,-2.93,;4.67,-1.39,;6,-.62,;3.33,-3.7,;2,-2.93,;.67,-3.7,;-.67,-2.93,;-.67,-1.39,;.67,-.62,;2,-1.39,;-2,-.62,;-3.33,-1.39,;-4.67,-.62,;-6,-1.39,;-7.34,-.62,;-7.34,.92,;-8.67,1.69,;-6,1.69,;-4.67,.92,;-3.33,1.69,;-2,.92,;-.67,1.69,;.8,1.21,;1.7,2.46,;3.24,2.46,;.8,3.7,;-.67,3.23,)| | ||
Structure |