| Reaction Details |
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 | Report a problem with these data |
| Target | Thyrotropin subunit beta |
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| Ligand | BDBM60862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Antagonist Activity Assay |
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| IC50 | 48±0.0 nM |
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| Citation |  Karstens, WF; Conti, PG; Timmers, CM; Plate, R; Van Koppen, CJ TSH receptor antagonizing tetrahydroquinoline compounds US Patent US9174940 Publication Date 11/3/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Thyrotropin subunit beta |
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| Name: | Thyrotropin subunit beta |
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| Synonyms: | TSHB | TSHB_BOVIN | Thyroid-stimulating hormone subunit beta (bTSH) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15628.77 |
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| Organism: | Bos taurus (Bovine) |
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| Description: | P01223 |
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| Residue: | 138 |
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| Sequence: | MTATFLMSMIFGLACGQAMSFCIPTEYMMHVERKECAYCLTINTTVCAGYCMTRDVNGKL
FLPKYALSQDVCTYRDFMYKTAEIPGCPRHVTPYFSYPVAISCKCGKCNTDYSDCIHEAI
KTNYCTKPQKSYMVGFSI
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| BDBM60862 |
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| n/a |
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| Name | BDBM60862 |
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| Synonyms: | BDBM189328 | US9174940, 32 |
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| Type | n/a |
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| Emp. Form. | C24H30N2O3 |
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| Mol. Mass. | 394.5066 |
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| SMILES | CC(=O)N1CCC(C)(C2C=C(NC(=O)OC3CCCC3)C=CC12)c1ccccc1 |c:21,t:9| |
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| Structure | 
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