| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serum paraoxonase/arylesterase 1 |
|---|
| Ligand | BDBM189358 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Paraoxonase Activity Assay |
|---|
| pH | 10.5±n/a |
|---|
| Ki | 8.973e+6± 9.55e+5 nM |
|---|
| IC50 | 2.3300e+7±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Alim, Z; Beydemir, S Some Anticancer Agents Act on Human Serum Paraoxonase-1 to Reduce Its Activity. Chem Biol Drug Des88:188-96 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serum paraoxonase/arylesterase 1 |
|---|
| Name: | Serum paraoxonase/arylesterase 1 |
|---|
| Synonyms: | A-esterase 1 | Aromatic esterase 1 | K-45 | PON | PON 1 | PON1 | PON1_HUMAN | Paraoxonase (PON1) | Paraoxonase (hPON1) | Paraoxonase 1 (PON1) | Serum aryldialkylphosphatase 1 | Serum paraoxonase 1 (PON1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39719.73 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P27169 |
|---|
| Residue: | 355 |
|---|
| Sequence: | MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
|
|
|
|---|
| BDBM189358 |
|---|
| n/a |
|---|
| Name | BDBM189358 |
|---|
| Synonyms: | Asta Z 4942 | Ifosfamide | Iphosphamide | N,3-bis(2-chloroethyl)-2-oxo-1,3,2-oxazaphosphinan-2-amine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C7H15Cl2N2O2P |
|---|
| Mol. Mass. | 261.086 |
|---|
| SMILES | ClCCNP1(=O)OCCCN1CCCl |
|---|
| Structure | 
|
|---|
Search and Browse
