| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome P450 3A5 |
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| Ligand | BDBM190404 |
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| Substrate/Competitor | US9180183, BFC |
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| Meas. Tech. | Fluorescent High Throughput P450 Assays |
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| Temperature | 310.15±n/a K |
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| IC50 | 10500±500 nM |
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| Comments | extracted |
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| Citation |  Maj, R; Pattarino, F; Mura, E; Barberis, A Phospholipid drug analogs US Patent US9180183 Publication Date 11/10/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome P450 3A5 |
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| Name: | Cytochrome P450 3A5 |
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| Synonyms: | CP3A5_HUMAN | CYP3A5 | Cytochrome P450 3A5 | Cytochrome P450 3A5 (CYP3A5) |
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| Type: | Protein |
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| Mol. Mass.: | 57118.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20815 |
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| Residue: | 502 |
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| Sequence: | MDLIPNLAVETWLLLAVSLVLLYLYGTRTHGLFKRLGIPGPTPLPLLGNVLSYRQGLWKF
DTECYKKYGKMWGTYEGQLPVLAITDPDVIRTVLVKECYSVFTNRRSLGPVGFMKSAISL
AEDEEWKRIRSLLSPTFTSGKLKEMFPIIAQYGDVLVRNLRREAEKGKPVTLKDIFGAYS
MDVITGTSFGVNIDSLNNPQDPFVESTKKFLKFGFLDPLFLSIILFPFLTPVFEALNVSL
FPKDTINFLSKSVNRMKKSRLNDKQKHRLDFLQLMIDSQNSKETESHKALSDLELAAQSI
IFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVV
NETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFS
KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG
LLQPEKPIVLKVDSRDGTLSGE
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| BDBM190404 |
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| US9180183, BFC |
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| Name | BDBM190404 |
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| Synonyms: | US9180183, SC12 |
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| Type | Small organic molecule |
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| Emp. Form. | C45H73N6O12P |
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| Mol. Mass. | 921.0679 |
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| SMILES | CCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCCNC(=O)c1ccc(Cn2c3nc(OCCOC)nc(N)c3[nH]c2=O)cc1)OC(=O)CCCCCCCCCCC |
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| Structure | 
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