| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
|---|
| Ligand | BDBM6644 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | KinaseGlo Plus Luminescent Assay |
|---|
| pH | 7.5±n/a |
|---|
| IC50 | 3.64e+4± 6.4e+3 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Ursu, A; Illich, DJ; Takemoto, Y; Porfetye, AT; Zhang, M; Brockmeyer, A; Janning, P; Watanabe, N; Osada, H; Vetter, IR; Ziegler, S; Schöler, HR; Waldmann, H Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol23:494-507 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform delta |
|---|
| Name: | Casein kinase I isoform delta |
|---|
| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 47356.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48730 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
|
|
|
|---|
| BDBM6644 |
|---|
| n/a |
|---|
| Name | BDBM6644 |
|---|
| Synonyms: | 6‐phenylpteridine‐2,4,7‐triamine (5) | 6-phenylpteridine-2,4,7-triamine | Pteridine deriv. 11 | TRIAMTERENE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H11N7 |
|---|
| Mol. Mass. | 253.2626 |
|---|
| SMILES | Nc1nc(N)c2nc(c(N)nc2n1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
