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TargetHepsin
LigandBDBM50013876
Substrate/Competitorn/a
Meas. Tech.High-Throughput Screening Assay
IC50 750±90 nM
Citation Vasioukhin VIChevillet JR Hepsin inhibitors US Patent  US9182402 Publication Date 11/10/2015
More Info.:Get all data from this article,  Assay Method
 
Hepsin
Name:Hepsin
Synonyms:Serine protease hepsin | Transmembrane protease, serine 1
Type:Enzyme
Mol. Mass.:45016.98
Organism:Homo sapiens (Human)
Description:Human deglycosylated hepsin was expressed in Pichia pastoris.
Residue:417
Sequence:
MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSAD
ARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCV
DEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSL
RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYH
GGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ
YYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCE
DSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
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  Blast E-value cutoff:
BDBM50013876
n/a
NameBDBM50013876
Synonyms:CHEMBL291278 | Methyl aspartic acid | N-Methyl aspartic acid | N-Methyl-D-aspartate | N-Methyl-D-aspartic acid | N-Methylaspartate | NMDA | US9182402, 16
TypeSmall organic molecule
Emp. Form.C5H9NO4
Mol. Mass.147.1293
SMILESCN[C@H](CC(O)=O)C(O)=O |r|
Structure
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