| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil collagenase |
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| Ligand | BDBM50092158 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro MMP-8 Assay |
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| Temperature | 310.15±n/a K |
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| IC50 | 35000±n/a nM |
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| Comments | extracted |
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| Citation |  Johnson, F; Golub, L Curcumin analogues as zinc chelators and their uses US Patent US9187406 Publication Date 11/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Neutrophil collagenase |
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| Name: | Neutrophil collagenase |
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| Synonyms: | CLG1 | MMP-8 | MMP8 | MMP8_HUMAN | Matrix metalloproteinase-8 | Neutrophil collagenase precursor | PMNL collagenase | PMNL-CL |
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| Type: | Enzyme |
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| Mol. Mass.: | 53413.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P22894 |
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| Residue: | 467 |
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| Sequence: | MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIV
EKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNY
TPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGIL
AHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYA
FRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKD
RYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQG
YPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGI
ESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
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|
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| BDBM50092158 |
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| n/a |
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| Name | BDBM50092158 |
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| Synonyms: | 1,10-phenanthroline | CHEMBL415879 | US10669227, Compound 1,10-phenanthroline | US11608309, Compound 1,10-phenanthroline | US9187406, 1,10-phenanthroline | cid_1318 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8N2 |
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| Mol. Mass. | 180.2053 |
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| SMILES | c1cnc2c(c1)ccc1cccnc21 |
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| Structure | 
|
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