| Reaction Details |
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 | Report a problem with these data |
| Target | Cytochrome b |
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| Ligand | BDBM192103 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cytochrome b Enzyme Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 449.1±n/a nM |
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| Comments | extracted |
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| Citation |  Vincent, BM; Langlois, JB; Srinivas, R; Lancaster, AK; Scherz-Shouval, R; Whitesell, L; Tidor, B; Buchwald, SL; Lindquist, S A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. Cell Chem Biol23:978-991 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytochrome b |
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| Name: | Cytochrome b |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 43717.83 |
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| Organism: | Candida albicans (Yeast) |
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| Description: | n/a |
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| Residue: | 387 |
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| Sequence: | MPTRKSNTYLSLVNSYLIDSPQPSSINYWWNLGSLLGLCLVIQIASGVFLAMHYSSNIEL
AFDSVEHIMRDVNAGWLIRYIHANGASFFFICMYLHIGKALYYGSYKQPRVMLWVIGVVI
FILTMAIAFMGYCLVYGQMSHWGATVITNLLSAIPFIGNDIVPFIWGGFSVSNPTIQRFF
ALHFLLPFILAALVCMHLMALHVHGSSNPVGITGNIDRLPMHPYFIFKDLITVFVFLLIF
SLFVFYSPNTLGHPDNYIPGNPMVTPPSIVPEWYLLPFYAILRSIPDKLGGVIAMFGAIL
ILLSLPYTDRSIIRGNSFKVLSKLAFYLFVFNFILLGNLGQLHVEVPYIQLGQFATAYYF
AHYIIVVPVISTLENILYYIGTQTRVK
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| BDBM192103 |
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| n/a |
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| Name | BDBM192103 |
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| Synonyms: | Inz-94 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H12F4N4 |
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| Mol. Mass. | 372.319 |
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| SMILES | Fc1ccc(cc1-c1nn(Cc2cnccn2)c2ccccc12)C(F)(F)F |
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| Structure | 
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