| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50399525 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Radioligand Displacement Assay (CP55940) |
|---|
| Ki | 23.91±n/a nM |
|---|
| Citation |  Maitra, R; Fulp, AB; Zhang, Y; Seltzman, HH Peripherally restricted diphenyl purine derivatives US Patent US9187480 Publication Date 11/17/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50399525 |
|---|
| n/a |
|---|
| Name | BDBM50399525 |
|---|
| Synonyms: | CHEMBL2180226 | US9187480, tert-butyl 4-{[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]amino}piperidine-1-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H28Cl2N6O2 |
|---|
| Mol. Mass. | 539.456 |
|---|
| SMILES | CC(C)(C)OC(=O)N1CCC(CC1)Nc1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
