| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Seed linoleate 13S-lipoxygenase-1 |
|---|
| Ligand | BDBM192765 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Lipo-oxygenase Inhibitory Assay |
|---|
| pH | 7±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | 5.2e+2± 1e+2 nM |
|---|
| Comments | extracted |
|---|
| Citation |  Jabbari, A; Sadeghian, H; Salimi, A; Mousavian, M; Seyedi, SM; Bakavoli, M 2-Prenylated m-dimethoxybenzenes as potent inhibitors of 15-lipo-oxygenase: inhibitory mechanism and SAR studies. Chem Biol Drug Des88:460-9 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Seed linoleate 13S-lipoxygenase-1 |
|---|
| Name: | Seed linoleate 13S-lipoxygenase-1 |
|---|
| Synonyms: | 15-LOX | 15-Lipo-oxygenase (15-LO) | 15-lipo-oxygenase (SLO) | Arachidonic Acid 15- Lipoxygenase | L-1 | LOX1 | LOX1.1 | LOX1_SOYBN | Lipoxygenase (LOX) | Lipoxygenase (SLO) | Lipoxygenase-1 | Seed lipoxygenase-1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 94365.66 |
|---|
| Organism: | Glycine max (soybean) |
|---|
| Description: | n/a |
|---|
| Residue: | 839 |
|---|
| Sequence: | MFSAGHKIKGTVVLMPKNELEVNPDGSAVDNLNAFLGRSVSLQLISATKADAHGKGKVGK
DTFLEGINTSLPTLGAGESAFNIHFEWDGSMGIPGAFYIKNYMQVEFFLKSLTLEAISNQ
GTIRFVCNSWVYNTKLYKSVRIFFANHTYVPSETPAPLVSYREEELKSLRGNGTGERKEY
DRIYDYDVYNDLGNPDKSEKLARPVLGGSSTFPYPRRGRTGRGPTVTDPNTEKQGEVFYV
PRDENLGHLKSKDALEIGTKSLSQIVQPAFESAFDLKSTPIEFHSFQDVHDLYEGGIKLP
RDVISTIIPLPVIKELYRTDGQHILKFPQPHVVQVSQSAWMTDEEFAREMIAGVNPCVIR
GLEEFPPKSNLDPAIYGDQSSKITADSLDLDGYTMDEALGSRRLFMLDYHDIFMPYVRQI
NQLNSAKTYATRTILFLREDGTLKPVAIELSLPHSAGDLSAAVSQVVLPAKEGVESTIWL
LAKAYVIVNDSCYHQLMSHWLNTHAAMEPFVIATHRHLSVLHPIYKLLTPHYRNNMNINA
LARQSLINANGIIETTFLPSKYSVEMSSAVYKNWVFTDQALPADLIKRGVAIKDPSTPHG
VRLLIEDYPYAADGLEIWAAIKTWVQEYVPLYYARDDDVKNDSELQHWWKEAVEKGHGDL
KDKPWWPKLQTLEDLVEVCLIIIWIASALHAAVNFGQYPYGGLIMNRPTASRRLLPEKGT
PEYEEMINNHEKAYLRTITSKLPTLISLSVIEILSTHASDEVYLGQRDNPHWTSDSKALQ
AFQKFGNKLKEIEEKLVRRNNDPSLQGNRLGPVQLPYTLLYPSSEEGLTFRGIPNSISI
|
|
|
|---|
| BDBM192765 |
|---|
| n/a |
|---|
| Name | BDBM192765 |
|---|
| Synonyms: | 1,3-Dimethoxy-5-methyl-2-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzene (11) |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H36O2 |
|---|
| Mol. Mass. | 356.5414 |
|---|
| SMILES | [#6]-[#8]-c1cc(-[#6])cc(-[#8]-[#6])c1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6] |
|---|
| Structure | 
|
|---|
Search and Browse
