| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
|---|
| Ligand | BDBM194512 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Competitive Binding Assay |
|---|
| IC50 | <10±n/a nM |
|---|
| Citation |  Natchus, MG; Arrendale, R; Liotta, D Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction US Patent US9205085 Publication Date 12/8/2015 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 4 |
|---|
| Name: | C-X-C chemokine receptor type 4 |
|---|
| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4/SDF-1) | CXCR4_RAT | Cmkar4 | Cxcr4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39342.13 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | O08565 |
|---|
| Residue: | 349 |
|---|
| Sequence: | MEIYTSDNYSEEVGSGDYDSNKEPCFRDENENFNRIFLPTIYFIIFLTGIVGNGLVILVM
GYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSS
VLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDIIFADVSQGDGR
YICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVI
LILAFFACWLPYYVGISIDSFILLEVIKQGCEFESVVHKWISITEALAFFHCCLNPILYA
FLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
|
|
|
|---|
| BDBM194512 |
|---|
| n/a |
|---|
| Name | BDBM194512 |
|---|
| Synonyms: | US9205085, MSX- 134 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H18N4 |
|---|
| Mol. Mass. | 290.3623 |
|---|
| SMILES | C(Nc1ccccn1)c1cccc(CNc2ccccn2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
