| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 4 |
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| Ligand | BDBM194578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Competitive Binding Assay |
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| IC50 | 100±n/a nM |
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| Citation |  Natchus, MG; Arrendale, R; Liotta, D Tricyclic amino containing compounds for treatment or prevention of symptoms associated with endocrine dysfunction US Patent US9205085 Publication Date 12/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 4 |
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| Name: | C-X-C chemokine receptor type 4 |
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| Synonyms: | C-X-C chemokine receptor type 4 | C-X-C chemokine receptor type 4 (CXCR4/SDF-1) | CXCR4_RAT | Cmkar4 | Cxcr4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39342.13 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | O08565 |
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| Residue: | 349 |
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| Sequence: | MEIYTSDNYSEEVGSGDYDSNKEPCFRDENENFNRIFLPTIYFIIFLTGIVGNGLVILVM
GYQKKLRSMTDKYRLHLSVADLLFVITLPFWAVDAMADWYFGKFLCKAVHIIYTVNLYSS
VLILAFISLDRYLAIVHATNSQRPRKLLAEKAVYVGVWIPALLLTIPDIIFADVSQGDGR
YICDRLYPDSLWMVVFQFQHIMVGLILPGIVILSCYCIIISKLSHSKGHQKRKALKTTVI
LILAFFACWLPYYVGISIDSFILLEVIKQGCEFESVVHKWISITEALAFFHCCLNPILYA
FLGAKFKSSAQHALNSMSRGSSLKILSKGKRGGHSSVSTESESSSFHSS
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| BDBM194578 |
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| n/a |
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| Name | BDBM194578 |
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| Synonyms: | US9205085, MSX- 212 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N4O |
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| Mol. Mass. | 292.3351 |
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| SMILES | C(Nc1ncccn1)c1ccc(COc2ccccn2)cc1 |
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| Structure | 
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