| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM194809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dopamine D2 Receptor Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 1.4±n/a nM |
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| Comments | extracted |
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| Citation |  Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Piperazine-substituted benzothiophenes for treatment of mental disorders US Patent US9206167 Publication Date 12/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM194809 |
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| n/a |
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| Name | BDBM194809 |
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| Synonyms: | US9206167, 31 | USRE48059, Compound of Example 31 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N3O2S |
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| Mol. Mass. | 449.608 |
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| SMILES | CCN1CCc2ccc(OCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O |
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| Structure | 
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