| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM194800 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Serotonin 5-HT2A Receptor Binding Assay |
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| pH | 7.4±n/a |
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| Temperature | 310.15±n/a K |
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| Ki | 1±n/a nM |
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| Comments | extracted |
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| Citation |  Yamashita, H; Ito, N; Miyamura, S; Oshima, K; Matsubara, J; Kuroda, H; Takahashi, H; Shimizu, S; Tanaka, T Piperazine-substituted benzothiophenes for treatment of mental disorders US Patent US9206167 Publication Date 12/8/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52852.05 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cortex membranes 5-HT2A receptors. |
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| Residue: | 471 |
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| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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|
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| BDBM194800 |
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| n/a |
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| Name | BDBM194800 |
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| Synonyms: | US9206167, 21 | USRE48059, Compound of Example 21 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H29N3OS |
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| Mol. Mass. | 419.582 |
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| SMILES | O=C1CCc2ccccc2N1CCCCN1CCN(CC1)c1cccc2sccc12 |
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| Structure | 
|
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