Reaction Details |
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Target | D-amino-acid oxidase |
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Ligand | BDBM50431074 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Inhibition Assay |
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pH | 7.5±n/a |
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Temperature | 298.15±n/a K |
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IC50 | 2.7±n/a nM |
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Comments | extracted |
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Citation | Hondo, T; Nakanishi, K; Niimi, T; Warizaya, M; Namatame, I; Harada, K Dihydroxy aromatic heterocyclic compound US Patent US9212147 Publication Date 12/15/2015 |
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More Info.: | Get all data from this article, Assay Method |
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D-amino-acid oxidase |
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Name: | D-amino-acid oxidase |
Synonyms: | D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN |
Type: | Homodimer |
Mol. Mass.: | 39476.06 |
Organism: | Homo sapiens (Human) |
Description: | P14920 |
Residue: | 347 |
Sequence: | MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPN
NPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPR
ELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVN
CTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG
IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGP
SNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
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BDBM50431074 |
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n/a |
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Name | BDBM50431074 |
Synonyms: | CHEMBL2338790 | US10463663, Example 27 | US11129828, Example 27 | US9212147, 254 | US9290456, 27 | US9931340, Example 27 |
Type | Small organic molecule |
Emp. Form. | C12H11ClN2O2 |
Mol. Mass. | 250.681 |
SMILES | Oc1cc(CCc2ccc(Cl)cc2)n[nH]c1=O |
Structure |
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