| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 (mGlu4) |
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| Ligand | BDBM196914 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pharmacological Assay |
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| EC50 | 530±120 nM |
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| Citation |  Acher F; Pin J; Goudet C; Eschalier A; Busserolles J; Rigault D; Lemasson I; Cesarini S; Commare B Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof US Patent US9212196 Publication Date 12/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 4 (mGlu4) |
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| Name: | Metabotropic glutamate receptor |
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| Synonyms: | GRM4 | Metabotropic glutamate receptor | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a |
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| Type: | Enzyme |
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| Mol. Mass.: | 101849.79 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P31423 |
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| Residue: | 912 |
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| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
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| BDBM196914 |
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| n/a |
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| Name | BDBM196914 |
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| Synonyms: | US9212196, Derivative 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22NO8P |
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| Mol. Mass. | 375.3108 |
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| SMILES | Cc1cc(cc(C)c1OCC(O)=O)C(O)P(O)(=O)CC[C@@H](N)C(O)=O |r| |
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| Structure | 
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