| Reaction Details |
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 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 8 |
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| Ligand | BDBM196909 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Pharmacological Assay |
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| EC50 | 3720±310 nM |
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| Citation |  Acher, F; Pin, J; Goudet, C; Eschalier, A; Busserolles, J; Rigault, D; Lemasson, I; Cesarini, S; Commare, B Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof US Patent US9212196 Publication Date 12/15/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Metabotropic glutamate receptor 8 |
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| Name: | Metabotropic glutamate receptor 8 |
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| Synonyms: | GRM8_RAT | Gprc1h | Grm8 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 8 (mGlu8) | Mglur8 | glutamate receptor, metabotropic 8 precursor | mGlu8 | metabotropic glutamate 8 |
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| Type: | Enzyme |
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| Mol. Mass.: | 101886.18 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P70579 |
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| Residue: | 908 |
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| Sequence: | MVCEGKRLASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER
GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV
QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA
PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR
EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS
GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA
EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH
KERCPGYIGLCPRMVTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQINN
KSTEYKIIGHWTNQLHLKVEDMQWANREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER
CEGYNYQVDELSCELCPLDQRPNINRTGCQRIPIIKLEWHSPWAVVPVFIAILGIIATTF
VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRIFLGLGMC
FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH
TIIDYGEQRTLDPENARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA
KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI
IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY
ISYSNHSI
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| BDBM196909 |
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| n/a |
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| Name | BDBM196909 |
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| Synonyms: | US9212196, Derivative 5 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19N2O11P |
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| Mol. Mass. | 422.2812 |
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| SMILES | COc1cc(cc(c1OCC(O)=O)[N+]([O-])=O)C(O)P(O)(=O)CC[C@@H](N)C(O)=O |r| |
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| Structure | 
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