Reaction Details |
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Target | Nicotinamide N-methyltransferase |
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Ligand | BDBM50047015 |
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Substrate/Competitor | n/a |
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Meas. Tech. | NNMT Enzymatic Activity Assay |
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pH | 8.6±n/a |
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Temperature | 310.15±n/a K |
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Ki | 102000000±33000000 nM |
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Comments | extracted |
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Citation | van Haren, MJ; Sastre Toraņo, J; Sartini, D; Emanuelli, M; Parsons, RB; Martin, NI A Rapid and Efficient Assay for the Characterization of Substrates and Inhibitors of Nicotinamide N-Methyltransferase. Biochemistry55:5307-15 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Nicotinamide N-methyltransferase |
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Name: | Nicotinamide N-methyltransferase |
Synonyms: | NNMT | NNMT_HUMAN | Nicotinamide N-methyltransferase | Nicotinamide N-methyltransferase (NNMT) |
Type: | Protein |
Mol. Mass.: | 29571.16 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 264 |
Sequence: | MESGFTSKDTYLSHFNPRDYLEKYYKFGSRHSAESQILKHLLKNLFKIFCLDGVKGDLLI
DIGSGPTIYQLLSACESFKEIVVTDYSDQNLQELEKWLKKEPEAFDWSPVVTYVCDLEGN
RVKGPEKEEKLRQAVKQVLKCDVTQSQPLGAVPLPPADCVLSTLCLDAACPDLPTYCRAL
RNLGSLLKPGGFLVIMDALKSSYYMIGEQKFSSLPLGREAVEAAVKEAGYTIEWFEVISQ
SYSSTMANNEGLFSLVARKLSRPL
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BDBM50047015 |
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n/a |
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Name | BDBM50047015 |
Synonyms: | CHEMBL14474 | Chinolin | benzo[b]pyridine | quinoline |
Type | Small organic molecule |
Emp. Form. | C9H7N |
Mol. Mass. | 129.1586 |
SMILES | c1ccc2ncccc2c1 |
Structure |
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