| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Histone deacetylase 7 |
|---|
| Ligand | BDBM197336 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | HDAC activity assays |
|---|
| IC50 | 3499.25±123.74 nM |
|---|
| Citation |  Miyake, Y; Keusch, JJ; Wang, L; Saito, M; Hess, D; Wang, X; Melancon, BJ; Helquist, P; Gut, H; Matthias, P Structural insights into HDAC6 tubulin deacetylation and its selective inhibition. Nat Chem Biol12:748-54 (2016) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Histone deacetylase 7 |
|---|
| Name: | Histone deacetylase 7 |
|---|
| Synonyms: | HD7 | HDAC7 | HDAC7A | HDAC7_HUMAN | Histone acetylase 7 (HDAC7) | Histone deacetylase 7A | Human HDAC7 |
|---|
| Type: | Chromatin regulator; hydrolase; repressor |
|---|
| Mol. Mass.: | 102942.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q8WUI4 |
|---|
| Residue: | 952 |
|---|
| Sequence: | MDLRVGQRPPVEPPPEPTLLALQRPQRLHHHLFLAGLQQQRSVEPMRLSMDTPMPELQVG
PQEQELRQLLHKDKSKRSAVASSVVKQKLAEVILKKQQAALERTVHPNSPGIPYRTLEPL
ETEGATRSMLSSFLPPVPSLPSDPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKE
SAPPSLRRRPAETLGDSSPSSSSTPASGCSSPNDSEHGPNPILGSEALLGQRLRLQETSV
APFALPTVSLLPAITLGLPAPARADSDRRTHPTLGPRGPILGSPHTPLFLPHGLEPEAGG
TLPSRLQPILLLDPSGSHAPLLTVPGLGPLPFHFAQSLMTTERLSGSGLHWPLSRTRSEP
LPPSATAPPPPGPMQPRLEQLKTHVQVIKRSAKPSEKPRLRQIPSAEDLETDGGGPGQVV
DDGLEHRELGHGQPEARGPAPLQQHPQVLLWEQQRLAGRLPRGSTGDTVLLPLAQGGHRP
LSRAQSSPAAPASLSAPEPASQARVLSSSETPARTLPFTTGLIYDSVMLKHQCSCGDNSR
HPEHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
NGKLAGLLAQRMFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELKNG
FAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQ
DPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRI
VVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALE
GGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQR
LASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
|
|
|
|---|
| BDBM197336 |
|---|
| n/a |
|---|
| Name | BDBM197336 |
|---|
| Synonyms: | R-TSA |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H22N2O3 |
|---|
| Mol. Mass. | 302.3682 |
|---|
| SMILES | C[C@H](\C=C\C(=O)NO)\C=C(/C)C(=O)c1ccc(cc1)N(C)C |r| |
|---|
| Structure | 
|
|---|
Search and Browse
