| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein phosphatase 2A activator |
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| Ligand | BDBM199180 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | PTP pNPP Assay |
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| pH | 7±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | >1000±0.0 nM |
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| Comments | extracted |
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| Citation |  Zhang, Z; Zhang, S Inhibitors of protein tyrosine phosphatases US Patent US9217012 Publication Date 12/22/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein phosphatase 2A activator |
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| Name: | Serine/threonine-protein phosphatase 2A activator |
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| Synonyms: | 5.2.1.8 | PPP2R4 | PTPA | PTPA_HUMAN | Phosphotyrosyl phosphatase activator | Protein phosphatase 2A regulatory subunit B | Protein phosphatase 2A regulatory subunit B' | Serine/threonine-protein phosphatase 2A activator | Serine/threonine-protein phosphatase 2A regulatory subunit 4 |
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| Type: | n/a |
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| Mol. Mass.: | 40662.53 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15257 |
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| Residue: | 358 |
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| Sequence: | MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
GKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLD
RWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGN
STRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAG
SQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKT
GPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG
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| BDBM199180 |
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| n/a |
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| Name | BDBM199180 |
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| Synonyms: | US9217012, 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C46H62F2N5O9P |
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| Mol. Mass. | 897.9831 |
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| SMILES | CCc1ccc(cc1)C(=O)NCCCCC(NC(=O)C(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)C(Cc1ccccc1)NC(=O)COC1CC(C)CCC1C(C)C)C(N)=O |
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| Structure | 
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