| Reaction Details |
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 | Report a problem with these data |
| Target | Protein mono-ADP-ribosyltransferase PARP10 [809-1017,S927A] |
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| Ligand | BDBM199181 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzymatic Activity Assay |
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| IC50 | 2.25e+3±n/a nM |
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| Citation |  Venkannagari, H; Verheugd, P; Koivunen, J; Haikarainen, T; Obaji, E; Ashok, Y; Narwal, M; Pihlajaniemi, T; Lüscher, B; Lehtiö, L Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. Cell Chem Biol23:1251-1260 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Protein mono-ADP-ribosyltransferase PARP10 [809-1017,S927A] |
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| Name: | Protein mono-ADP-ribosyltransferase PARP10 [809-1017,S927A] |
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| Synonyms: | Human diphtheria toxin-like ADP-ribosyltransferase (S927A) (ARTD10 or PARP10(S927A)) | PAR10_HUMAN | PARP10 |
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| Type: | n/a |
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| Mol. Mass.: | 23404.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q53GL7[809-1017,S927A] |
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| Residue: | 209 |
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| Sequence: | AGQTLKGPWNNLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELY
RERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRAALSV
QDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIF
VIFHDTQALPTHLITCEHVPRASPDDPSG
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| BDBM199181 |
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| n/a |
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| Name | BDBM199181 |
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| Synonyms: | 4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carboxamide (OUL35) |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N2O3 |
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| Mol. Mass. | 256.2567 |
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| SMILES | NC(=O)c1ccc(Oc2ccc(cc2)C(N)=O)cc1 |
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| Structure | 
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