| Reaction Details |
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 | Report a problem with these data |
| Target | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 |
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| Ligand | BDBM200908 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assay (Method B) |
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| IC50 | 100±n/a nM |
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| Citation |  Bystrom, S; Hedgecock, C; Homan, E; Lundback, T; Martinsson, J; Sari, M; Farnegardh, K; Jonsson, M Sulfonamide compounds US Patent US9233946 Publication Date 1/12/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 |
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| Name: | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 |
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| Synonyms: | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) | F264_HUMAN | PFKFB4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 54039.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16877 |
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| Residue: | 469 |
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| Sequence: | MASPRELTQNPLKKIWMPYSNGRPALHACQRGVCMTNCPTLIVMVGLPARGKTYISKKLT
RYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSE
EGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYV
NRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVY
YLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVW
TSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRY
PKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTV
LKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
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| BDBM200908 |
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| n/a |
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| Name | BDBM200908 |
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| Synonyms: | US9233946, 7 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N2O4S3 |
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| Mol. Mass. | 396.504 |
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| SMILES | CC(C)c1ccc2sc(c(C)c2c1)S(=O)(=O)Nc1ncc(s1)C(O)=O |
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| Structure | 
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