| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 1 |
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| Ligand | BDBM203319 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | IMAP Assay |
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| IC50 | 0.65±n/a nM |
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| Citation |  Shipps, Jr., GW; Deng, Y; Cooper, AB; Gao, X; Sun, B; Wang, J; Zhu, L Fused pyrazole derivatives as novel ERK inhibitors US Patent US9242981 Publication Date 1/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 1 |
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| Name: | Mitogen-activated protein kinase 1 |
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| Synonyms: | ERT1 | Erk2 | Extracellular signal-regulated kinase 2 | Extracellular signal-regulated kinase 2 (ERK2) | MAP kinase 1 | MAP kinase 2 | MAP kinase ERK2 | MAPK 1 | MAPK 2 | MK01_MOUSE | Mapk | Mapk1 | Mitogen-activated protein kinase 2 | Prkm1 | p42 | p42-MAPK |
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| Type: | Protein |
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| Mol. Mass.: | 41278.65 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P63085 |
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| Residue: | 358 |
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| Sequence: | MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQ
TYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLS
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG
FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG
ILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRI
EVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
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| BDBM203319 |
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| n/a |
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| Name | BDBM203319 |
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| Synonyms: | US9242981, 48 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27FN6O |
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| Mol. Mass. | 434.5092 |
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| SMILES | Fc1ccccc1CN1CCC[C@H](C1)NC(=O)N1CCc2[nH]nc(c2C1)-c1ccncc1 |r| |
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| Structure | 
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