| Reaction Details |
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 | Report a problem with these data |
| Target | Apoptosis regulator Bcl-2 [1-204] |
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| Ligand | BDBM156402 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Polarization Assay |
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| pH | 7.5±n/a |
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| IC50 | 0.4±n/a nM |
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| Comments | extracted |
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| Citation |  Diebold, RB; Gero, TW; Grover, P; Huang, S; Ioannidis, S; Ogoe, CA; Saeh, JC Chemical compounds US Patent US9248140 Publication Date 2/2/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Apoptosis regulator Bcl-2 [1-204] |
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| Name: | Apoptosis regulator Bcl-2 [1-204] |
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| Synonyms: | Apoptosis regulator Bcl-2 | BCL2 | BCL2_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 22461.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | C-terminal 6XHIS tagged Bcl-2 (aa 1-204) |
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| Residue: | 204 |
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| Sequence: | MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
LNRHLHTWIQDNGGWDAFVELYGP
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| BDBM156402 |
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| n/a |
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| Name | BDBM156402 |
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| Synonyms: | US9018381, 25 | US9248140, 25 |
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| Type | Small organic molecule |
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| Emp. Form. | C47H50ClF3N4O8S3 |
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| Mol. Mass. | 987.565 |
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| SMILES | OC[C@H]1COCCN1CC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(CC1)[C@@H](O)c1ccccc1-c1ccc(Cl)cc1 |r| |
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| Structure | 
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