| Reaction Details |
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 | Report a problem with these data |
| Target | Inorganic pyrophosphatase |
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| Ligand | BDBM205470 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric Malachite Green Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 4.4e+4± 5e+3 nM |
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| Comments | extracted |
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| Citation |  Pang, AH; Garzan, A; Larsen, MJ; McQuade, TJ; Garneau-Tsodikova, S; Tsodikov, OV Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis. ACS Chem Biol11:3084-3092 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Inorganic pyrophosphatase |
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| Name: | Inorganic pyrophosphatase |
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| Synonyms: | IPYR_MYCTU | Inorganic pyrophosphatase | Inorganic pyrophosphatase (MtPPiase) | PPase | Pyrophosphate phospho-hydrolase | ppa |
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| Type: | Protein |
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| Mol. Mass.: | 18318.35 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WI55 |
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| Residue: | 162 |
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| Sequence: | MQFDVTIEIPKGQRNKYEVDHETGRVRLDRYLYTPMAYPTDYGFIEDTLGDDGDPLDALV
LLPQPVFPGVLVAARPVGMFRMVDEHGGDDKVLCVPAGDPRWDHVQDIGDVPAFELDAIK
HFFVHYKDLEPGKFVKAADWVDRAEAEAEVQRSVERFKAGTH
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| BDBM205470 |
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| n/a |
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| Name | BDBM205470 |
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| Synonyms: | PPiase inhibitor, 14 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H46N6 |
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| Mol. Mass. | 502.7371 |
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| SMILES | CCCCCCN(CCCCCC)c1nc(nc(n1)-c1cccn1-c1ccccc1)N1CCCCCC1 |
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| Structure | 
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