| Reaction Details |
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 | Report a problem with these data |
| Target | Inorganic pyrophosphatase |
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| Ligand | BDBM205466 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Colorimetric Malachite Green Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 4.55e+5± 4.0e+4 nM |
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| Comments | extracted |
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| Citation |  Pang, AH; Garzan, A; Larsen, MJ; McQuade, TJ; Garneau-Tsodikova, S; Tsodikov, OV Discovery of Allosteric and Selective Inhibitors of Inorganic Pyrophosphatase from Mycobacterium tuberculosis. ACS Chem Biol11:3084-3092 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Inorganic pyrophosphatase |
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| Name: | Inorganic pyrophosphatase |
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| Synonyms: | IPP1 | IPYR_YEAST | Inorganic pyrophosphatase (ScPPiase) | PPA | PPA1 |
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| Type: | Protein |
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| Mol. Mass.: | 32294.13 |
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| Organism: | Saccharomyces cerevisiae (Yeast) |
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| Description: | P00817 |
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| Residue: | 287 |
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| Sequence: | MTYTTRQIGAKNTLEYKVYIEKDGKPVSAFHDIPLYADKENNIFNMVVEIPRWTNAKLEI
TKEETLNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPNVSHPETKAVGDNDPI
DVLEIGETIAYTGQVKQVKALGIMALLDEGETDWKVIAIDINDPLAPKLNDIEDVEKYFP
GLLRATNEWFRIYKIPDGKPENQFAFSGEAKNKKYALDIIKETHDSWKQLIAGKSSDSKG
IDLTNVTLPDTPTYSKAASDAIPPASPKADAPIDKSIDKWFFISGSV
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| BDBM205466 |
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| n/a |
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| Name | BDBM205466 |
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| Synonyms: | PPiase inhibitor, 9 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H32N6 |
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| Mol. Mass. | 416.5618 |
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| SMILES | C1CCCN(CC1)c1nc(nc(n1)-c1cccn1-c1ccccc1)N1CCCCCC1 |
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| Structure | 
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