| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50015011 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Ligand Binding Assays |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 0.16±n/a nM |
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| Comments | extracted |
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| Citation |  Lewis, J; Husbands, S Orvinol and thevinol derivatives useful in the treatment of depression US Patent US9259422 Publication Date 2/16/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
|
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|
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| BDBM50015011 |
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| n/a |
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| Name | BDBM50015011 |
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| Synonyms: | CHEMBL3262363 | US9259422, 7a, 2-MePh- BU10101 | US9480684, 7a, 2- MePh- BU10101 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H39NO4 |
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| Mol. Mass. | 501.6564 |
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| SMILES | [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@]([H])(C1)[C@](C)(O)c1ccccc1C)ccc3O |r,THB:10:9:17:4.5.6| |
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| Structure | 
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