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TargetBeta-2 adrenergic receptor
LigandBDBM50213120
Substrate/Competitorn/a
Meas. Tech.Beta2-AR Binding Assay
pH7.7±n/a
Kd 1950±n/a nM
Commentsextracted
Citation Wainer, IWBernier, MToll, LRJimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent US9492405 Publication Date 11/15/2016
More Info.:Get all data from this article,  Assay Method
 
Beta-2 adrenergic receptor
Name:Beta-2 adrenergic receptor
Synonyms:ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:n/a
Mol. Mass.:46461.69
Organism:Homo sapiens (Human)
Description:P07550
Residue:413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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  Blast E-value cutoff:
BDBM50213120
n/a
NameBDBM50213120
Synonyms:(R,S)-(-)-1-p-methoxyphenyl-2-(beta-3',5'-dihydroxyphenyl-beta-oxy)ethylaminopropane | CHEMBL228996 | US10617654, Compound (R,S)-2 | US9249163, 33 | US9492405, (R,S)-2
TypeSmall organic molecule
Emp. Form.C18H23NO4
Mol. Mass.317.3795
SMILESCOc1ccc(C[C@H](C)NC[C@H](O)c2cc(O)cc(O)c2)cc1
Structure
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