| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50213098 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mitogenesis inhibition method |
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| Temperature | 310.15±n/a K |
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| IC50 | 0.14±0.07 nM |
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| Comments | extracted |
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| Citation |  Wainer, IW; Bernier, M; Toll, LR; Jimenez, LA Use of fenoterol and fenoterol analogues in the treatment of glioblastomas and astrocytomas US Patent US9492405 Publication Date 11/15/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50213098 |
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| n/a |
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| Name | BDBM50213098 |
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| Synonyms: | (R,R)-(-)-fenoterol | CHEMBL388570 | US10617654, Compound (R,R)-1 | US9492405, (R,R)-1 | US9492405, 28 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21NO4 |
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| Mol. Mass. | 303.3529 |
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| SMILES | C[C@H](Cc1ccc(O)cc1)NC[C@H](O)c1cc(O)cc(O)c1 |
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| Structure | 
|
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