| Reaction Details |
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 | Report a problem with these data |
| Target | Putative FAD-containing monooxygenase MymA |
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| Ligand | BDBM50336507 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MymA Inhibition Assay |
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| IC50 | 4.9e+3±n/a nM |
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| Citation |  Saraav, I; Pandey, K; Misra, R; Singh, S; Sharma, M; Sharma, S Characterization of MymA protein as a flavin-containing monooxygenase and as a target of isoniazid. Chem Biol Drug Des89:152-160 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Putative FAD-containing monooxygenase MymA |
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| Name: | Putative FAD-containing monooxygenase MymA |
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| Synonyms: | MYMA_MYCTU | mymA |
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| Type: | Protein |
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| Mol. Mass.: | 55489.29 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | P9WNF7 |
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| Residue: | 495 |
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| Sequence: | MNQHFDVLIIGAGLSGIGTACHVTAEFPDKTIALLERRERLGGTWDLFRYPGVRSDSDMF
TFGYKFRPWRDVKVLADGASIRQYIADTATEFGVDEKIHYGLKVNTAEWSSRQCRWTVAG
VHEATGETRTYTCDYLISCTGYYNYDAGYLPDFPGVHRFGGRCVHPQHWPEDLDYSGKKV
VVIGSGATAVTLVPAMAGSNPGSAAHVTMLQRSPSYIFSLPAVDKISEVLGRFLPDRWVY
EFGRRRNIAIQRKLYQACRRWPKLMRRLLLWEVRRRLGRSVDMSNFTPNYLPWDERLCAV
PNGDLFKTLASGAASVVTDQIETFTEKGILCKSGREIEADIIVTATGLNIQMLGGMRLIV
DGAEYQLPEKMTYKGVLLENAPNLAWIIGYTNASWTLKSDIAGAYLCRLLRHMADNGYTV
ATPRDAQDCALDVGMFDQLNSGYVKRGQDIMPRQGSKHPWRVLMHYEKDAKILLEDPIDD
GVLHFAAAAQDHAAA
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| BDBM50336507 |
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| n/a |
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| Name | BDBM50336507 |
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| Synonyms: | 4-pyridinecarbohydrazide(Isoniazid) | CHEMBL64 | Dow-isoniazid | Hyzyd | INH | ISONICOTINIC ACID HYDRAZIDE(ISONIAZIDE) | Isoniazid (INH) | Isonicotinic acid hydrazide (Isoniazid) | Isonicotinic acid hydrazide(Isoniazid) | Isonicotinylhydrazine | Laniazid | Nydrazid | Rimifon | Stanozide | isoniazid | isonicotinamide | isonicotinhydrazide | isonicotinohydrazide | isonicotinyl hydrazide | pyridine-4-carbohydrazide |
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| Type | Small organic molecule |
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| Emp. Form. | C6H7N3O |
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| Mol. Mass. | 137.1393 |
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| SMILES | NNC(=O)c1ccncc1 |
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| Structure | 
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