| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 7 |
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| Ligand | BDBM209414 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In vitro Erk5 |
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| Kd | 320±n/a nM |
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| Citation |  Gray, NS; Deng, X; Kwiatkowski, NP Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders US Patent US9266890 Publication Date 2/23/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitogen-activated protein kinase 7 |
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| Name: | Mitogen-activated protein kinase 7 |
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| Synonyms: | BMK1 | Big MAP kinase 1 | ERK5 | Extracellular signal-regulated kinase 5 (ERK5) | MAPK7 | MK07_HUMAN | PRKM7 |
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| Type: | Protein |
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| Mol. Mass.: | 88377.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13164 |
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| Residue: | 816 |
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| Sequence: | MAEPLKEEDGEDGSAEPPGPVKAEPAHTAASVAAKNLALLKARSFDVTFDVGDEYEIIET
IGNGAYGVVSSARRRLTGQQVAIKKIPNAFDVVTNAKRTLRELKILKHFKHDNIIAIKDI
LRPTVPYGEFKSVYVVLDLMESDLHQIIHSSQPLTLEHVRYFLYQLLRGLKYMHSAQVIH
RDLKPSNLLVNENCELKIGDFGMARGLCTSPAEHQYFMTEYVATRWYRAPELMLSLHEYT
QAIDLWSVGCIFGEMLARRQLFPGKNYVHQLQLIMMVLGTPSPAVIQAVGAERVRAYIQS
LPPRQPVPWETVYPGADRQALSLLGRMLRFEPSARISAAAALRHPFLAKYHDPDDEPDCA
PPFDFAFDREALTRERIKEAIVAEIEDFHARREGIRQQIRFQPSLQPVASEPGCPDVEMP
SPWAPSGDCAMESPPPAPPPCPGPAPDTIDLTLQPPPPVSEPAPPKKDGAISDNTKAALK
AALLKSLRSRLRDGPSAPLEAPEPRKPVTAQERQREREEKRRRRQERAKEREKRRQERER
KERGAGASGGPSTDPLAGLVLSDNDRSLLERWTRMARPAAPALTSVPAPAPAPTPTPTPV
QPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQIATS
TSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKS
QVEDPLPPVFSGTPKGSGAGYGVGFDLEEFLNQSFDMGVADGPQDGQADSASLSASLLAD
WLEGHGMNPADIESLQREIQMDSPMLLADLPDLQDP
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| BDBM209414 |
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| n/a |
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| Name | BDBM209414 |
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| Synonyms: | US9266890, I-24 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H28N6O2 |
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| Mol. Mass. | 420.5074 |
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| SMILES | CN1c2cnc(Nc3ccc(cc3)C(N)=O)nc2N(C2CCCC2)[C@@H]2CCC[C@@H]2C1=O |r| |
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| Structure | 
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