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TargetProtein tyrosine phosphatase 1B (PTP1B)
LigandBDBM50327036
Substrate/Competitorn/a
Meas. Tech.PTP1B Inhibition Assay
Ki 8.200e+6± 4.00e+5 nM
Citation Lipchock JMHendrickson HPDouglas BBBird KEGinther PSRivalta ITen NSBatista VSLoria JP Characterization of Protein Tyrosine Phosphatase 1B Inhibition by Chlorogenic Acid and Cichoric Acid. Biochemistry 56:96-106 (2017) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Protein tyrosine phosphatase 1B (PTP1B)
Name:Protein tyrosine phosphatase 1B (PTP1B)
Synonyms:n/a
Type:Protein
Mol. Mass.:35009.03
Organism:Homo sapiens (Human)
Description:PTP1B truncation (1-301 aa)
Residue:301
Sequence:
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLH
QEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLK
CAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWP
DFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKD
PSSVDIKKVLLEMRKFRMGLIQTADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLE
P
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  Blast E-value cutoff:
BDBM50327036
n/a
NameBDBM50327036
Synonyms:(1R,3S,4S,5S)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid | (1S,3R,4R,5R)-3-[(E)-3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid | (1S,3R,4R,5R,E)-3-(3-(3,4-dihydroxyphenyl)acryloyloxy)-1,4,5-trihydroxycyclohexanecarboxylic acid | 3-[(E)-3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid | 3-[3-(3,4-Dihydroxy-phenyl)-acryloyloxy]-1,4,5-trihydroxy-cyclohexanecarboxylic acid | 5-O-caffeoylquinic acid | 5-caffeoyl quinic acid | CHEMBL284616 | Caffeoylquinic acid | Chlorogenic acid (CGA) | Chlorogenicacid | NSC-407296 | chlorogenic acid
TypeSmall organic molecule
Emp. Form.C16H18O9
Mol. Mass.354.3087
SMILESO[C@@H]1C[C@](O)(C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@@H]1O)C(O)=O |r|
Structure
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