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TargetProstaglandin E2 receptor EP3 subtype
LigandBDBM50095293
Substrate/Competitorn/a
Meas. Tech.EP3 Radioligand SPA Binding Assay
pH7.4±n/a
Temperature298.15±n/a K
Ki 31.6±n/a nM
Commentsextracted
Citation Bahnck, KBEdmonds, DJFutatsugi, KLee, ECMathiowetz, AMMenhaji-Klotz, EStanton, RV Antagonists of prostaglandin EP3 receptor US Patent US9278953 Publication Date 3/8/2016
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP3 subtype
Name:Prostaglandin E2 receptor EP3 subtype
Synonyms:PE2R3_HUMAN | PGE receptor, EP3 subtype | PGE2-R | PTGER3 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostaglandin E2 receptor EP3A subtype (EP3A) | Prostaglandin E2 receptor EP3D subtype (EP3D) | Prostanoid EP3 receptor
Type:Enzyme
Mol. Mass.:43335.03
Organism:Homo sapiens (Human)
Description:P43115
Residue:390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
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BDBM50095293
n/a
NameBDBM50095293
Synonyms:CHEMBL3589085 | US9278953, 13
TypeSmall organic molecule
Emp. Form.C20H22N4O2
Mol. Mass.350.4143
SMILESCCn1ncc2c(C)cc(cc12)-c1ccc(c(=O)[nH]1)[C@@]1(C)CCNC1=O |r|
Structure
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