| Reaction Details |
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 | Report a problem with these data |
| Target | Acetyl-CoA carboxylase 2 [129-967] |
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| Ligand | BDBM212612 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Spectrophotometric 384 Well Assay |
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| pH | 7.5±n/a |
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| IC50 | 118±n/a nM |
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| Comments | extracted |
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| Citation |  Heine, N; Fleck, M; Nosse, B; Roth, GJ Pyrrolidine derivatives, pharmaceutical compositions and uses thereof US Patent US9278954 Publication Date 3/8/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Acetyl-CoA carboxylase 2 [129-967] |
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| Name: | Acetyl-CoA carboxylase 2 [129-967] |
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| Synonyms: | ACACB | ACACB_HUMAN | ACC2 | ACCB | Acetyl-CoA carboxylase 2 (ACC2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 92599.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O00763 lacks the 128 amino acids at the N-terminus |
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| Residue: | 839 |
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| Sequence: | DTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSVAGSSREST
RKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPA
EFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANA
EYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG
VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDV
YDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSP
IFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFME
QCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIA
MGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGT
VQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG
DFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFR
TCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEID
AHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQY
TVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPS
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| BDBM212612 |
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| n/a |
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| Name | BDBM212612 |
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| Synonyms: | US9278954, 1.3 | US9278954, 1.4 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33FN4O2 |
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| Mol. Mass. | 440.5535 |
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| SMILES | CCCNc1nccc(N2CC[C@H](C2)Oc2ccc(cc2)C(C)C(=O)NC2CC2C)c1F |r| |
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| Structure | 
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