| Reaction Details |
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 | Report a problem with these data |
| Target | C-terminal-binding protein 1 [V66R] |
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| Ligand | BDBM213227 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Equilibrium Dialysis |
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| Kd | 5e+2±n/a nM |
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| Citation |  Madison, DL; Wirz, JA; Siess, D; Lundblad, JR Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan. J Biol Chem288:27836-48 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-terminal-binding protein 1 [V66R] |
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| Name: | C-terminal-binding protein 1 [V66R] |
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| Synonyms: | C-terminal binding protein (CtBP1 V66R) | CTBP | CTBP1 | CTBP1_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 47595.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human CtBP1 V66R mutant |
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| Residue: | 440 |
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| Sequence: | MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQ
EIHEKRLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNV
PAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGII
GLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLN
EHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFS
QGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAAT
HWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHA
PSPGQTVKPEADRDHASDQL
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| BDBM213227 |
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| n/a |
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| Name | BDBM213227 |
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| Synonyms: | Nicotinamide adenine dinucleotide (NAD) |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27N7O14P2 |
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| Mol. Mass. | 663.4251 |
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| SMILES | NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |
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| Structure | 
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