| Reaction Details |
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 | Report a problem with these data |
| Target | Macrophage-stimulating protein receptor [983-1400,G1195S] |
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| Ligand | BDBM213708 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 4.3±0.0 nM |
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| Comments | extracted |
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| Citation |  Staehle, W; Schadt, O; Knuehl, C; Friese-Hamim, M; Huck, BR; Goutopoulos, A; Brugger, N Pyrido-pyrimidine derivatives US Patent US9283225 Publication Date 3/15/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Macrophage-stimulating protein receptor [983-1400,G1195S] |
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| Name: | Macrophage-stimulating protein receptor [983-1400,G1195S] |
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| Synonyms: | MST1R | Macrophage-stimulating protein receptor (RON) | PTK8 | RON | RON_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 47287.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | MST1R (RON) recombinant human protein (Life Technologies, 983-1400 aa) |
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| Residue: | 418 |
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| Sequence: | RRKQLVLPPNLNDLASLDQTAGATPLPILYSGSDYRSGLALPAIDGLDSTTCVHGASFSD
SEDESCVPLLRKESIQLRDLDSALLAEVKDVLIPHERVVTHSDRVIGKGHFGVVYHGEYI
DQAQNRIQCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHVLLP
YMCHGDLLQFIRSPQRNPTVKDLISFGLQVARSMEYLAEQKFVHRDLAARNCMLDESFTV
KVADFGLARDILDREYYSVQQHRHARLPVKWMALESLQTYRFTTKSDVWSFGVLLWELLT
RGAPPYRHIDPFDLTHFLAQGRRLPQPEYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVE
QIVSALLGDHYVQLPATYMNLGPSTSHEMNVRPEQPQFSPMPGNVRRPRPLSEPPRPT
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| BDBM213708 |
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| n/a |
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| Name | BDBM213708 |
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| Synonyms: | US9283225, A1 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H16F4N6O3 |
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| Mol. Mass. | 512.4159 |
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| SMILES | Fc1cc(NC(=O)c2cnn(c2C(F)(F)F)-c2ccccc2)ccc1Oc1ccnc2NC(=O)NCc12 |
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| Structure | 
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