| Reaction Details |
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 | Report a problem with these data |
| Target | Catenin beta-1 [138-686] |
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| Ligand | BDBM50392084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AlphaScreen Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 24390±740 nM |
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| Comments | extracted |
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| Citation |  Ji, H; Yu, B; Zhang, M; Guo, W Substituted 1H-indazol-1-ol analogs as inhibitors of beta catenin/Tcf protein-protein interactions US Patent US9284299 Publication Date 3/15/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Catenin beta-1 [138-686] |
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| Name: | Catenin beta-1 [138-686] |
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| Synonyms: | Beta-catenin | CTNB1_HUMAN | CTNNB | CTNNB1 |
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| Type: | Protein |
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| Mol. Mass.: | 60127.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | aa 138-686 |
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| Residue: | 549 |
|---|
| Sequence: | NLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSA
IVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAIT
TLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILA
SGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRL
VQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMM
VCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKL
LHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQ
QQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGV
LCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVE
LTSSLFRTE
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|
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| BDBM50392084 |
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| n/a |
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| Name | BDBM50392084 |
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| Synonyms: | CHEMBL2152586 | US9284299, PNU-74654 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11NO2 |
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| Mol. Mass. | 213.2319 |
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| SMILES | NC(=O)c1ccccc1Oc1ccccc1 |
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| Structure | 
|
|---|
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