Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Isoform Tau-F of Microtubule-associated protein tau | ||
| Ligand | BDBM50241461 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Tau Protein Assay | ||
| pH | 7.4±n/a | ||
| IC50 | 6.1e+2± 5e+1 nM | ||
| Comments | extracted | ||
| Citation |  Schafer, KN; Cisek, K; Huseby, CJ; Chang, E; Kuret, J Structural determinants of Tau aggregation inhibitor potency. J Biol Chem288:32599-611 (2013) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Isoform Tau-F of Microtubule-associated protein tau | |||
| Name: | Isoform Tau-F of Microtubule-associated protein tau | ||
| Synonyms: | MAPT | MAPTL | MTBT1 | Microtubule-associated protein | Microtubule-associated protein Tau isoform 2N4R (Tau 2N4R) | Microtubule-associated protein tau (TAU)(2N4R) | TAU | TAU_HUMAN | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 45857.42 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P10636-8 | ||
| Residue: | 441 | ||
| Sequence: |
| ||
| BDBM50241461 | |||
| n/a | |||
| Name | BDBM50241461 | ||
| Synonyms: | 3,7-bis(dimethylamino)phenothiazin-5-ium chloride | Basic Blue 9 | CHEMBL405110 | Methylenblau | Methylene Blue anhydrous | Methylene blue | Methylene blue (10) | SAMPL5, CBC-G10 | azul de metileno | bleu de methylene | cid_6099 | methylthioninium chloride | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H18N3S | ||
| Mol. Mass. | 284.399 | ||
| SMILES | CN(C)c1ccc2nc3ccc(cc3sc2c1)=[N+](C)C |(17.73,-40.24,;19.06,-41.01,;19.06,-42.55,;20.39,-40.24,;20.4,-38.7,;21.73,-37.93,;23.06,-38.69,;24.39,-37.91,;25.73,-38.69,;27.06,-37.93,;28.39,-38.69,;28.39,-40.23,;27.06,-41,;25.73,-40.23,;24.39,-41.01,;23.06,-40.24,;21.73,-41.01,;29.73,-41,;29.73,-42.54,;31.06,-40.23,)| | ||
| Structure | 
| ||