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TargetBifunctional epoxide hydrolase 2
LigandBDBM50327816
Substrate/Competitorn/a
Meas. Tech.Fluorescent Based Assay
pH7±n/a
IC50 1.4±n/a nM
Commentsextracted
Citation Hammock, BDRose, TMorisseau, CLee, KS Acyl piperidine inhibitors of soluble epoxide hydrolase US Patent US9296693 Publication Date 3/29/2016
More Info.:Get all data from this article,  Assay Method
 
Bifunctional epoxide hydrolase 2
Name:Bifunctional epoxide hydrolase 2
Synonyms:Eph2 | Ephx2 | Epoxide hydratase | HYES_MOUSE | Soluble epoxide hydrolase (sEH)
Type:Enzyme
Mol. Mass.:62512.06
Organism:Mus musculus (Mouse)
Description:P34914
Residue:554
Sequence:
MALRVAAFDLDGVLALPSIAGAFRRSEEALALPRDFLLGAYQTEFPEGPTEQLMKGKITF
SQWVPLMDESYRKSSKACGANLPENFSISQIFSQAMAARSINRPMLQAAIALKKKGFTTC
IVTNNWLDDGDKRDSLAQMMCELSQHFDFLIESCQVGMIKPEPQIYNFLLDTLKAKPNEV
VFLDDFGSNLKPARDMGMVTILVHNTASALRELEKVTGTQFPEAPLPVPCNPNDVSHGYV
TVKPGIRLHFVEMGSGPALCLCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSSSP
PEIEEYAMELLCKEMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVRAVASLNTPF
MPPDPDVSPMKVIRSIPVFNYQLYFQEPGVAEAELEKNMSRTFKSFFRASDETGFIAVHK
ATEIGGILVNTPEDPNLSKITTEEEIEFYIQQFKKTGFRGPLNWYRNTERNWKWSCKGLG
RKILVPALMVTAEKDIVLRPEMSKNMEKWIPFLKRGHIEDCGHWTQIEKPTEVNQILIKW
LQTEVQNPSVTSKI
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BDBM50327816
n/a
NameBDBM50327816
Synonyms:1-(4-Iodophenyl)-3-(1-propionylpiperidin-4-yl)urea | CHEMBL1258337 | US9296693, 27
TypeSmall organic molecule
Emp. Form.C15H20IN3O2
Mol. Mass.401.2427
SMILESCCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(I)cc1
Structure
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