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TargetSulfotransferase 2A1 (SULT2A1)
LigandBDBM22870
Substrate/Competitorn/a
Meas. Tech.Amoxapine and Protriptyline Inhibition Assay
pH7.5±n/a
Temperature275.15±n/a K
Ki 1.25e+5± 1.06e+4 nM
Commentsextracted
Citation Cook IWang TFalany CNLeyh TS High accuracy in silico sulfotransferase models. J Biol Chem 288:34494-501 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Sulfotransferase 2A1 (SULT2A1)
Name:Sulfotransferase 2A1 (SULT2A1)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:33776.92
Organism:Homo sapiens (Human)
Description:Q06520
Residue:285
Sequence:
MSDDFLWFEGIAFPTMGFRSETLRKVRDEFVIRDEDVIILTYPKSGTNWLAEILCLMHSK
GDAKWIQSVPIWERSPWVESEIGYTALSETESPRLFSSHLPIQLFPKSFFSSKAKVIYLM
RNPRDVLVSGYFFWKNMKFIKKPKSWEEYFEWFCQGTVLYGSWFDHIHGWMPMREEKNFL
LLSYEELKQDTGRTIEKICQFLGKTLEPEELNLILKNSSFQSMKENKMSNYSLLSVDYVV
DKAQLLRKGVSGDWKNHFTVAQAEDFDKLFQEKMADLPRELFPWE
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  Blast E-value cutoff:
BDBM22870
n/a
NameBDBM22870
Synonyms:13-chloro-10-(piperazin-1-yl)-2-oxa-9-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,9,12,14-heptaene | 2-chloro-11-piperazin-1-yldibenzo[b,f][1,4]oxazepine | Amoxapine | Asendin | CHEMBL1113 | Demolox
TypeSmall organic molecule
Emp. Form.C17H16ClN3O
Mol. Mass.313.781
SMILESClc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1 |t:13|
Structure
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