Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetM3 muscarinic receptor (M3'(3C)-Xa T552C)
LigandBDBM50004656
Substrate/Competitorn/a
Meas. Tech.[3H]NMS/Carbachol Binding Assay
pH7.4±n/a
Ki 1.46e+4± 2.3e+3 nM
Commentsextracted
Citation Hu JHu KLiu TStern MKMistry RChalliss RACostanzi SWess J Novel structural and functional insights into M3 muscarinic receptor dimer/oligomer formation. J Biol Chem 288:34777-90 (2013) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
M3 muscarinic receptor (M3'(3C)-Xa T552C)
Name:M3 muscarinic receptor (M3'(3C)-Xa T552C)
Synonyms:n/a
Type:Protein
Mol. Mass.:45888.21
Organism:Rattus norvegicus (Rat)
Description:Rat M3'(3C)-Xa with T552C mutation
Residue:405
Sequence:
MTLHSQSTTSPLFPQISSSWVHSPSEAGLPLGTVTQLGSYQISQETGQFSSQDTSSDPLG
GHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLASADLIIGVIS
MNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRT
TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFY
MPVTIMTILYWRIYKETEKRTKELAGLQASGTEIEGRIEGRIEGRTRSQITKRKRMSLIK
EKKAAQTLSAILLAFIITWTPYNIMVLVNTFADSAIPKTYWNLGYWLCYINSTVNPVAYA
LSNKTFRCTFKTLLLSQSDKRKRRKQQYQQRQSVIFHKRVPEQAL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50004656
n/a
NameBDBM50004656
Synonyms:(2-Carbamoyloxy-ethyl)-trimethyl-ammonium | (2-Carbamoyloxyethyl)trimethylammonium chloride | (2-Hydroxyethyl)trimethyl ammonium chloride carbamate | (2-Hydroxyethyl)trimethylammonium chloride carbamate | (carbachol)(2-Carbamoyloxy-ethyl)-trimethyl-ammonium | 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride | 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminum chloride | 2-(carbamoyloxy)-N,N,N-trimethylethanaminium | 2-(carbamoyloxy)-N,N,N-trimethylethanaminium chloride | CARBACHOL | CARBASTAT | CHEMBL14 | Carbachol chloride | Carbamylcholine | Choline carbamate chloride | Choline chloride, carbamate | Choline chlorine carbamate | Karbachol | Karbamoylcholin chlorid | MIOSTAT
TypeSmall organic molecule
Emp. Form.C6H15N2O2
Mol. Mass.147.195
SMILESC[N+](C)(C)CCOC(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: