| Reaction Details |
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 | Report a problem with these data |
| Target | Plasminogen [101-181] |
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| Ligand | BDBM290286 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biacore Assay |
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| pH | 7±n/a |
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| IC50 | 13.0±n/a nM |
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| Comments | extracted |
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| Citation |  Haßfeld, J; Kinzel, T; Köbberling, J; Cancho-Grande, Y; Beyer, K; Röhrig, S; Köllnberger, M; Sperzel, M; Burkhardt, N; Schlemmer, K; Stegmann, C; Schuhmacher, J; Werner, M; Ellermann, M (Aza)pyridopyrazolopyrimidinones and indazolopyrimidinones and their use US Patent US10098883 Publication Date 10/16/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Plasminogen [101-181] |
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| Name: | Plasminogen [101-181] |
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| Synonyms: | PLG | PLMN_HUMAN | Plasminogen (aa 101-181) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 9281.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00747[101-181] |
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| Residue: | 81 |
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| Sequence: | SECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYCRNPDNDPQ
GPWCYTTDPEKRYDYCDILEC
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|
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| BDBM290286 |
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| n/a |
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| Name | BDBM290286 |
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| Synonyms: | 7-Bromo-4-(piperidin-4-yl)pyrido[4′,3′:3,4]pyrazolo[1,5-a]pyrimidin-2(1H)-one hydrochloride | US10098883, Example 27 | US10668071, Example 27 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14BrN5O |
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| Mol. Mass. | 348.198 |
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| SMILES | Brc1cncc2c1nn1c(cc(=O)[nH]c21)C1CCNCC1 |
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| Structure | 
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