| Reaction Details |
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 | Report a problem with these data |
| Target | Trans-sialidase [3-643] |
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| Ligand | BDBM50048093 |
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| Substrate/Competitor | BDBM217357 |
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| Meas. Tech. | Diffusion Ordered Spectroscopy (DOSY) |
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| Temperature | 284.15±n/a K |
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| Kd | 1.5e+4± 1e+3 nM |
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| Comments | extracted |
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| Citation |  Oliveira, IA; Gonçalves, AS; Neves, JL; von Itzstein, M; Todeschini, AR Evidence of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis. J Biol Chem289:423-36 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trans-sialidase [3-643] |
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| Name: | Trans-sialidase [3-643] |
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| Synonyms: | trans-Sialidase (TS) |
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| Type: | Enzyme |
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| Mol. Mass.: | 70309.23 |
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| Organism: | Trypanosoma cruzi |
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| Description: | Q9BHJ5 with +2 shift |
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| Residue: | 641 |
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| Sequence: | APGSSRVELFKRKNSTVPFEDKAGKVTERVVHSFRLPALVNVDGVMVAIADARYDTSNDN
SLIDTVAKYSVDDGETWETQIAIKNSRVSSVSRVVDPTVIVKGNKLYVLVGSYYSSRSYW
SSHGDARDWDILLAVGEVTKSIAGGKITASIKWGSPVSLKKFFPAEMEGMHTNQFLGGAG
VAIVASNGNLVYPVQVTNKRKQVFSKIFYSEDDGKTWKFGKGRSDFGCSEPVALEWEGKL
IINTRVDWKRRLVYESSDMGNTWVEAVGTLSRVWGPSPKSDHPGSQSSFTAVTIEGMRVM
LFTHPLNFKGRWLRDRLNLWLTDNQRIYNVGQVSIGDENSAYSSVLYKDDKLYCLHEINT
DEVYSLVFARLVGELRIIKSVLRSWKNWDSHLSSICTPADPAASSSESGCGPAVTTVGLV
GFLSGNASQNVWEDAYRCVNASTANAERVRNGLKFAGVGGGALWPVSQQGQNQRYRFANH
AFTLVASVTIHEAPRAASPLLGASLDSSGGKKLLGLSYDEKHQWQPIYGSTPVTPTGSWE
TGKRYHVVLTVANKIGSVYIDGELLEGSGQTVVPDGRTPDISHFYVGGYGRSDMPTISHV
TVNNVLLYNRQLNTEEIRTLFLSQDLIGTEAHMDSSSDTSA
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| BDBM50048093 |
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| BDBM217357 |
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| Name | BDBM50048093 |
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| Synonyms: | CHEBI:610092 | CHEMBL503075 | Lactoside | Methyl Beta-D-Lactoside |
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| Type | Small organic molecule |
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| Emp. Form. | C13H24O11 |
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| Mol. Mass. | 356.3231 |
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| SMILES | CO[C@@H]1O[C@H](CO)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O |r| |
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| Structure | 
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