| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 11 |
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| Ligand | BDBM50380399 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC Activity Assay |
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| pH | 8±n/a |
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| IC50 | 3790±n/a nM |
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| Comments | extracted |
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| Citation |  Kozikowski, A; Kalin, JH; Butler, KV; Bergman, J; Hancock, WW HDAC inhibitors and therapeutic methods using the same US Patent US9249087 Publication Date 2/2/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Histone deacetylase 11 |
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| Name: | Histone deacetylase 11 |
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| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 39187.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96DB2 |
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| Residue: | 347 |
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| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
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|
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| BDBM50380399 |
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| n/a |
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| Name | BDBM50380399 |
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| Synonyms: | CHEMBL2018302 | Tubastatin A | US10227295, Compound Tubastatin A | US10456394, Tubastatin A | US11207431, Example D | US8748451, 6 | US9249087, Tubacin | US9751832, Tubastatin A | US9956192, Compound Tubastatin-A |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O2 |
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| Mol. Mass. | 335.3996 |
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| SMILES | CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO |
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| Structure | 
|
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