| Reaction Details |
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 | Report a problem with these data |
| Target | S-methyl-5'-thioinosine phosphorylase |
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| Ligand | BDBM218673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| Ki | 0.072±0.002 nM |
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| Comments | extracted |
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| Citation |  Schramm, VL; Clinch, K; Tyler, PC; Evans, GB; Furneaux, RH Methods, assays and compounds for treating bacterial infections by inhibiting methylthioinosine phosphorylase US Patent US9290501 Publication Date 3/22/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| S-methyl-5'-thioinosine phosphorylase |
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| Name: | S-methyl-5'-thioinosine phosphorylase |
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| Synonyms: | MTIP_PSEAE | S-methyl-5'-thioinosine phosphorylase (MTIP) |
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| Type: | Enzyme |
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| Mol. Mass.: | 26266.70 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | Q9HZK1 |
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| Residue: | 245 |
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| Sequence: | MSVYAIIGGTGLTQLEGLTLSESLPIETPYGAPSAPLQRGRYAGREVLFLARHGHPHRFP
PHQVNYRANLWALKQAGAEAVIAVNAVGGIHAAMGTGHLCVPHQLIDYTSGREHTYFAGD
IEHVTHIDFSHPYDEPLRQRLIEALRALGLAHSSHGVYACTQGPRLETVAEIARLERDGN
DIVGMTGMPEAALARELDLPYACLALVVNPAAGKSAGIITMAEIEQALHDGIGKVREVLA
RVLAG
|
|
|
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| BDBM218673 |
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| n/a |
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| Name | BDBM218673 |
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| Synonyms: | US9290501, PrT-DADMe-ImmH |
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| Type | Small organic molecule |
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| Emp. Form. | C15H22N4O2S |
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| Mol. Mass. | 322.426 |
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| SMILES | CCCSC[C@H]1CN(Cc2c[nH]c3c2nc[nH]c3=O)CC1O |r| |
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| Structure | 
|
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