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TargetCasein kinase II subunit beta
LigandBDBM218953
Substrate/CompetitorBDBM220103
Meas. Tech.Inhibition Assay
pH7±n/a
IC50 815.2±n/a nM
Commentsextracted
Citation Haddach, MTran, JAPierre, FRegan, CFRaffaele, NRavula, SRyckman, DM Pyrazolopyrimidines and related heterocycles as CK2 inhibitors US Patent US9303033 Publication Date 4/5/2016
More Info.:Get all data from this article,  Assay Method
 
Casein kinase II subunit beta
Name:Casein kinase II subunit beta
Synonyms:CK2N | CSK2B_HUMAN | CSNK2B | Casein kinase II subunit beta | Casein kinase II subunit beta (CK2 beta) | Casein kinase II subunit beta (CK2β) | G5A | Serine/threonine-protein kinase pim-2
Type:Enzyme
Mol. Mass.:24937.13
Organism:Homo sapiens (Human)
Description:P67870
Residue:215
Sequence:
MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDE
ELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPML
PIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPA
NQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
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  Blast E-value cutoff:
BDBM218953
BDBM220103
NameBDBM218953
Synonyms:US9303033, H5, Table 15A, Compound 1
TypeSmall organic molecule
Emp. Form.C20H17N5O3S
Mol. Mass.407.446
SMILESCOc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1
Structure
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