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TargetAldo-keto reductase family 1 member C1
LigandBDBM50396691
Substrate/Competitorn/a
Meas. Tech.Discontinuous Radiometric Assay
Ki 106000±n/a nM
Citation Penning TMAdeniji AOBurns MCWinkler JTwenter B Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof US Patent  US9271961 Publication Date 3/1/2016
More Info.:Get all data from this article,  Assay Method
 
Aldo-keto reductase family 1 member C1
Name:Aldo-keto reductase family 1 member C1
Synonyms:20-alpha-HSD | 20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) | Aldo-keto reductase family 1 member C1 (AK1C1) | Aldo-keto reductase family 1 member C1 (AK1C1a) | Aldo-keto reductase family 1 member C1 (AKR1C1) | Chlordecone reductase homolog HAKRC | High-affinity hepatic bile acid-binding protein | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
Type:Enzyme
Mol. Mass.:36793.97
Organism:Homo sapiens (Human)
Description:Recombinant AKR1C1 enzyme was expressed in E. coli.
Residue:323
Sequence:
MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPV
SVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLN
RNVRYLTLDIFAGPPNYPFSDEY
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BDBM50396691
n/a
NameBDBM50396691
Synonyms:CHEMBL449572 | US9271961, Jasmonic acid
TypeSmall organic molecule
Emp. Form.C12H18O3
Mol. Mass.210.2695
SMILESCC\C=C/C[C@@H]1[C@@H](CC(O)=O)CCC1=O |r|
Structure
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