| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 (BRD4) |
|---|
| Ligand | BDBM220611 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Bromodomain Domain Binding Assay |
|---|
| pH | 6±n/a |
|---|
| Temperature | 298.15±n/a K |
|---|
| Ki | 1.1±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Wang L; Pratt JK; McDaniel KF; Dai Y; Fidanze SD; Hasvold L; Holms JH; Kati WM; Liu D; Mantei RA; McClellan WJ; Sheppard GS; Wada CK Bromodomain inhibitors US Patent US9296741 Publication Date 3/29/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bromodomain-containing protein 4 (BRD4) |
|---|
| Name: | Bromodomain-containing protein 4 (BRD4) |
|---|
| Synonyms: | Bromodomain-containing protein 4 (BRD4-BD2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 12432.37 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | BD2: amino acids E352-M457 bromodomains of human BRD4 |
|---|
| Residue: | 106 |
|---|
| Sequence: | EQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEARE
YRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM
|
|
|
|---|
| BDBM220611 |
|---|
| n/a |
|---|
| Name | BDBM220611 |
|---|
| Synonyms: | US9296741, 200 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23N3O3S |
|---|
| Mol. Mass. | 385.48 |
|---|
| SMILES | CCS(=O)(=O)c1ccc(NCC2CC2)c(c1)-c1cn(C)c(=O)c2[nH]ccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
