| Reaction Details |
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 | Report a problem with these data |
| Target | Arginase-2, mitochondrial |
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| Ligand | BDBM290425 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay of Arginase |
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| pH | 7.4±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 625±n/a nM |
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| Comments | extracted |
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| Citation |  Van Zandt, M; Jagdmann, GE Arginase inhibitors as therapeutics US Patent US10098902 Publication Date 10/16/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Arginase-2, mitochondrial |
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| Name: | Arginase-2, mitochondrial |
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| Synonyms: | ARG2 | ARGI2_HUMAN | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38576.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_978892 |
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| Residue: | 354 |
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| Sequence: | MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
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| BDBM290425 |
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| n/a |
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| Name | BDBM290425 |
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| Synonyms: | (1S,2S,4S)-1,4-diamino-2-(3-boronopropyl)cyclopentanecarboxylic acid | US10098902, Example 61 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H23BN2O4 |
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| Mol. Mass. | 246.112 |
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| SMILES | CC(OO)[C@]1(N)C[C@@H](N)C[C@@H]1CCCB(O)O |r| |
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| Structure | 
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